Starting Wegovy: a Beginner’s Guide and Timeline
Understanding Semaglutide: What to Expect Medically
Starting semaglutide often feels like stepping into a guided experiment: a weekly injection gradually reduces appetite, slows stomach emptying and improves blood sugar control. Clinically, expect measurable changes in cravings and portion sizes within weeks, but weight responses vary and require close follow-up and dose adjustments.
Common side effects include nausea, constipation or diarrhea and transient fatigue; these usually ease with dose titration. Blood tests and thyroid checks advised before and during treatment. Report severe abdominal pain, palpitations or symptoms promptly, and combine therapy with dietary changes for best outcomes.
| Area | Note |
|---|---|
| Mechanism | GLP-1 receptor agonist; reduces appetite, slows gastric emptying |
| Monitoring | Weight, glucose, renal and thyroid function; watch for GI effects |
Preparing for Treatment: Medical Screening and Approvals

I sat in the clinic, anxious but hopeful, while the nurse reviewed my history and medications. They explained baseline tests A1c, liver panel, and renal function to ensure semaglutide suitability before beginning treatment and consent.
The clinician discussed benefits, risks, and alternatives, asking about pregnancy plans and pancreatitis history. I learned insurers often require prior authorization for wegovy, so financial counseling and documented weight-history are practical preparation steps and paperwork.
Before approval, baseline measurements blood pressure, ECG if indicated, and pregnancy tests for women establish safety. Photographs and weight charts create a clear baseline, helping clinicians monitor response and adjust the dosing schedule accurately safely.
Education covered injection technique, storage instructions, and recognizing side effects. We scheduled close follow-ups during titration and were given emergency contacts. Enrollment in support groups and pharmacist consultations eased my path into long-term management ahead.
Week-by-week Dosing Schedule and Titration Timeline
Starting on wegovy often feels like stepping into a guided climb rather than a sprint. Your clinician will outline a gradual dose increase over several weeks to help your body adjust and reduce nausea.
Typical titration moves from a low starter dose to intermediate and therapeutic doses every four weeks, though timing can vary. Expect regular check-ins and possible pauses if side effects emerge.
Keep a diary of dose, symptoms and appetite changes; adjustments make big difference. With patience, most people reach maintenance dosing within three months and notice progress.
Weight-loss Milestones: Realistic Expectations and Tracking

Starting with realistic goals keeps motivation steady; many see 4 to 7 percent weight loss in three months with wegovy, a promising signal; medical check ins confirm safety.
Track weekly weight and measurements rather than daily swings; trends tell the story; use an app or journal.
Plateaus are normal; expect slower loss after initial weeks. Discuss adjustments with your clinician; adapt calorie, activity, and dosing routines.
Celebrate non scale wins like energy, sleep, and confidence; set new targets every month to stay engaged and track long term progress; schedule reviews.
Managing Side Effects: Common Problems and Solutions
I remember the first week on wegovy: nausea arrived like a minor storm that passed with patience and small changes. Expect early GI symptoms and keep a simple food log to spot triggers and adjustments.
Constipation, heartburn and headaches are common but manageable. Increase water and fiber gradually, try smaller meals, and use antacids or analgesics as needed. Communicate persistent or severe issues to your clinician promptly for guidance always.
Timing and dose adjustments help. If injection timing causes discomfort, try evening doses. Slowly titrating per plan reduces intensity; report dizziness, palpitations, or mood swings. Review current prescriptions for interactions before starting and monitoring regularly.
Small practical tools matter: ginger, bland snacks, oral rehydration, and short walks ease symptoms. Keep a symptom diary, seek support groups, and remember adaptation takes weeks. With patience and teamwork, many find side effects fade.
| Symptom | Quick Fix |
|---|---|
| Nausea | Ginger, small bland meals |
| Constipation | Hydration, gradual fiber |
| Heartburn | Smaller meals, antacids |
Lifestyle Habits, Diet Tweaks, and Long-term Maintenance
When I began treatment, small daily routines made the biggest difference: swapping sugary snacks for protein-rich choices steadied my appetite and energy; prioritizing sleep consistently helped regulate hunger.
Consistent meal timing and hydration reduce nausea and help portion control; aim for balanced plates with vegetables, lean protein, and whole grains, not severe restriction and limit liquid calories.
Track progress with photos, measurements, and weekly weigh-ins rather than daily obsession. Milestone successes keep motivation high and reveal trends. Celebrate non-scale victories, too, regularly.
Plan for maintenance by building sustainable habits: enjoy occasional treats, practice mindful eating, schedule regular activity you like, and keep in touch with your provider for long-term adjustments. Have relapse plans ready, always.